This doc would not incorporate all achievable Unwanted effects and Other people may possibly manifest. Verify along with your physician For added specifics of Unintended effects.
Observe infants exposed to therapy via breast milk for excess sedation and respiratory despair; withdrawal signs can come about in breastfed infants when maternal administration of hydromorphone is stopped, or when breast-feeding is stopped
Availability of naloxone for emergency treatment of opioid overdose Means differ on how to receive naloxone as permitted by personal point out dispensing and prescribing specifications or recommendations (eg, by prescription, straight from a pharmacist, as A part of a Group-primarily based method)
Stay clear of use when getting any oral drug that is definitely dependent on threshold concentrations for efficacy. Interactions mentioned are consultant examples and don't consist of all feasible scientific examples.
Reserve concomitant prescribing of such medicines in clients for whom other procedure selections are inadequate. Limit dosages and durations for the bare minimum necessary. Monitor carefully for signs of respiratory melancholy and sedation.
To reduce the risk of respiratory despair, proper dosing and titration of DILAUDID INJECTION is crucial [see DOSAGE AND ADMINISTRATION]. Overestimating the DILAUDID INJECTION dosage when converting sufferers from A further opioid solution may end up in a deadly overdose with the main dose.
Serotonin syndrome: Cases of serotonin syndrome, a possibly existence-threatening problem, are reported during concomitant usage of opioids with serotonergic prescription drugs.
Reserve concomitant prescribing of such medicine in people for whom other treatment method options are insufficient. Restrict dosages and durations on the minimal demanded. Observe closely for indications of respiratory melancholy and sedation.
People today addicted to Dilaudid typically want to relive the euphoric and relaxed emotions they this contact form initially experienced Together with the drug, in order that they continue on attempting to copy this “rush.” This typically contributes to abusing more difficult medication, like heroin, that are generally additional available.
Cure of Overdose In case of overdose, priorities will be the reestablishment of the patent airway and protected airway and establishment of assisted or managed ventilation, if wanted. Hire other supportive actions (such as oxygen and vasopressors) from the management of circulatory shock and pulmonary edema as indicated. Cardiac arrest or arrhythmias will require Sophisticated everyday living-assistance procedures. The opioid antagonists, naloxone or nalmefene are distinct antidotes to respiratory despair resulting from opioid overdose. For clinically important respiratory or circulatory depression secondary to hydromorphone overdose, administer an opioid antagonist. Opioid antagonists really should not be administered from the absence of clinically major respiratory or circulatory despair secondary to hydromorphone overdose. As the length of opioid reversal is expected being fewer than the period of hydromorphone in DILAUDID INJECTION, diligently keep an eye on the client until eventually spontaneous respiration is reliably reestablished.
The usage of DILAUDID INJECTION is not encouraged for individuals having MAOIs or within just fourteen times of stopping this sort of cure.
Reserve concomitant prescribing of such medication in people for whom other cure choices are inadequate. Restrict dosages and durations on the bare minimum required. Monitor closely for signs of respiratory despair and sedation.
Opioid use boosts the possibility of CSA inside of a dose-dependent trend. In clients who present with CSA, think about lowering the opioid dosage applying very best tactics for opioid taper [see DOSAGE AND ADMINISTRATION].
The oral solution or tablets are contraindicated in individuals with regarded or suspected gastrointestinal obstruction, which include paralytic ileus; may perhaps bring about spasm of sphincter of Oddi; opioids may perhaps cause increases in serum amylase; keep an eye on sufferers with biliary tract ailment, like acute pancreatitis, for worsening indicators